-

,

— 1996.

26. 1. , 1996 .

Donald R.A. Uges, University Hospital Groningen, The Netherland

, /
( - , - )
, / ( - , - )

Acebutolol

336.4

C

0.5-1.25

L2.0

diaceton

308.4

C

0.65-4.5

-

Acenocoumarol

353.3

C

T0.03-0.09
P 0.1-0.5

T0.1-0.15

Acetaldehyde

44.1

K

0-30

100-125

Acetazolamide

1

222.2

C

(5) 10-20

25

Acetohexamide

324.4

C

20-55

-

Acetone

2

58.1

K

5-20

200-400
L550

Acetonitrile

41.1

K

-

L0.77

cyanide

42

-

-

Acetylsalicylic acid

3

180.2

C

salicylic acid

59

138.1

C

30-300

400-500
300
L500-900

Acyclovir

4

225.2

C

T0.5-1.5
P5-15

-

Ajmaline

326.4

C

0.2-1

-

Albendazole

265.3

albendazole sulphoxide

C

0.5-1.5

-

Aldrin

364.9

C

0-0.0015

0.0035

Alfentanil

416.5

C

0.03-0.6

-

Alimemazine

298.4

C

0.05-0.4

0.5

Allobarbital

208.2

C

5-10

20-30

Allopurinol

136.1

C

P1-5

-

oxypurinol

152.1

C

5-15

20

Alphaprodine

261.4

C

0.87-1.0

-

Alprazolam

308.8

C

0.02-0.06

0.1-0.4

Alprenolol

249.4

C

0.05-0.1

T0.1 P1

hydroxyalprenolol

C

0.04-0.065 - 0.1-0.2

T0.25-0.3

Aluminium

5

27.0

C

0-0.02 (0.1)

0.15

Amantadine

151.3

C

0.3-0.6

1

Amikacin

585.6

C

T1-4(8)
P15-25 (30)

T10 P35

Aminoglutethimide

232.3

C

0.5-25

-

4-Aminopyridine

94.1

C

0.025-0.075

0.15-0.2

Amiodarone

645.3

C

1-2.5 T0.5-2

3

desethylamiodarone

C

1-5

5-8

Amitriptyline

277.4

C

0.05-0.2

-

nortriptyline

263.4

C

0.12-0.25

0.5 L2

Ammonia

17.0

0.5-1.7

-

Amobarbital

226.3

C

1-5

10-30 L13-96

Amoxapine

313.8

C

0.01-0.2

L3

8-hydroamoxapine

0.2-0.4

-

Amoxicillin

6

365.4

C

T0.5-1 P5-15

-

Amphetamine

135.2

C

0.05-0.15

0.2-1 L>1

Amphotericin B

924.1

C

T0.025-1 P1.5-3.5

T5-10

Ampicillin

6

349/4

C

T0.02-1
P2-20

-

Amsacrine

7

393.5

C

0.1-0.5 T0.03
P0.15-5.5

-

Anileridine

352.5

C

-

L0.9

Aniline

93.1

C

-

L6

Apomorphine

267.3

C

0.002-0.02

-

Aprindine

322.5

C

0.75-2.5

2

Arsenic

8

74.9

K

0.002-0.07

0.1-0.25(1) L9-15

Arsenic

74.9

M

0-0.1

0.2-1

Atenolol

266.3

C

0.2-0.6 (1)

2

Atracurium

931.2

C

0.1-1 (5)

-

Atropine

289.4

C

0.002-0.025

0.02-0.03 L0.2

Azathioprine

9

277.3

C

P0.05-0.3

-

mercaptopurine

152.2

C

0.04-0.3

1-2

Aztreonam

435.4

C

T1-10
P50-250

-

Baclofen

213.7

C

0.2-0.6

1.1-3.5

Barbital

184.2

C

10-40

60-80 L>100

Barbiturates

.

1-5

10-30 L>30

.

10-40

40-60 L>80

C

1-5

7-10 L>10-15

Benzobromaron

424.1

C

2-10

-

Benzene ()

78.1

K

-

L0.95

Benzphetamine

239.4

C

0.025-0.5

0.5

Benztropine

307.4

C

0.08-0.125

0.05 L0.7

Betaxolol

307.4

C

0.005-0.05

-

Bethanidine

177.0

C

0.02-0.5

-

Biperiden

311.5

C

0.05-0.1

-

Bismuth

290.0

C

0-0.05

0.1

Bisoprolol

383

C

0.01-0.06

-

Boron

10.8

C

0.8-6

20-50 L50-150

Brallobarbital

287.1

C

4-8

10 L30

Brodifacoum

523.4

C

-

0.02

Bromadiolon

527.4

C

-

0.02

Bromazepam

316.2

C

0.08-0.17

0.25-0.5

Bromide

10

79.9

C

3-30 . 75-100 (300)

500-1000 (1500) L2000

Bromisoval

223.1

C

10-20

30-40

Bromperidol

11

420.3

C

0.002-0.02

-

Brompheniramine

319.2

C

0.008-0.015

-

Brotizolam

393.7

C

0.001-0.02

-

Bupivacaine

12

288.4

C

0.25-3
P1-4

4-10

Bupropion

239/7

C

0.025-0.1

-

Buspirone

385.5

C

0.0009-0.005 (0.01)

-

Butabarbital (Secbutobarbital)

212.2

C

1-5

10 (30) L>30

Butalbatal

224.3

C

1-10

7-15 L15-30

Butaperazine

409.0

C

0.02-0.7

-

Butobarbital

212.2

C

5-15

20

Butorphanol

327.5

C

0.0011-0.0017

-

Butriptyline

293.5

C

0.07-0.15

0.4

Cadmium

112.4

K

0-0.0065

0.015-0.05

Cadmium

112.4

M

0-0.005 / g creatinine

-

Caffeine

13

194.2

C

8-15 (2-10)

20-30 (50) L>80-100

Camazepam

371.8

C

0.1-0.6

2

Captopril

217.3

C

0.05-0.5

-

Carbamazepine

14

236.3

C

4.5-9 (12)

(12)-15 L>25

Carbamazepine-epoxide

C

0.5-3

15

Carbimazole

186.2

-

-

methimazole

C

T0.5-2.5

-

Carbon monoxide ( )

15

28

K

1-5%

25-35% L50-60%

Carbon tetrachloride

152.8

-

20-50 L100-200

Carboplatin (. )

371.3

platinum

195.1

C

P10-25

T0.1-0.2

Carbromal

237.1

C

5-10

15-20

bromide

79.9

C

5-30

400

Carisoprodol

260.3

C

10-40

30-50 L110

Cefaclor

6

358.8

C

oral.13-35 / 900

-

Cefamandole

6

462.5

C

T1-5 P10-40

-

Cefotaxime

6

477.5

C

T0.5-2
P10-50
/ 225

-

Cefsulodin

6

554.5

C

20-100

-

Ceftazidime

6

546.6

C

T20-40
P50-200

-

Ceftriaxone

6

598.5

C

15-75 -

-

Cefuroxime

6

424

C

T0.5-1
P10-60
/ 180

-

Cephaloridine

6

415.5

C

T0.5-1
P10-50

-

Cephradine

6

349.4

C

T0.5-1
P20-50

-

Chloral hydrate

165.4

trichloroetanol ()

149.4

C

(2) 5-15

40-70(100)

L200-250

Chloramphenicon

323.1

C

5-15
T5-10
P10-20(25)

25 T10

Chlordane

409.8

0.001

0.0025 L1-7

Chlordiazepoxide

299.8

C

0.7-2 (3)

3.5-10 L20

demoxepam

286.7

C

0.3-2.8

-

Chlormezanone

27.3

C

2.5-9

20

Chloroform

119.4

20-50

70-250 L390

Chlorophenoxyacetic acid

C

-

200

Chloroprocaine

270.8

2.4

-

Chloroquine

319.9

C

0.02-0.4

0.5-1 (2) L3

Chlorothiazide

295.7

C

6

-

Chlorpheniramine

274

C

0.017

20-30

Chlorphentermine

183

C

0.032

-

Chlorpromazine

318.9

C

0.05-0.5
0.04-0.08

(0.5) 1 (2) L3

Chlorpropamide

276

30-200

200-750

Chlorprothixene

315.9

C

0.03-0.3

0.7 (0.4-0.8)

Chlorthalidone

338.8

C

5-10
0.2-1.4

-

Cholinesterase Pseudo

C

2000-7000 M/L

1000 M/L

Cimetidine

252.3

C

0.5-1

1.25

Ciprofloxacin

385.8

C

0.4-4 T0.05-0.5
P1-5

-

Cisplatin (. )

300.1

P1-5

T0.1

platinum

195.1

C

P10-25

T0.1-0.2

Clobazam

16

300.7

0.1-0.4

-

N-desmethylclobazam

C

2-4

-

Clofibrat

242

C

50-250

-

Clomipramine

314.9

0.05-0.15

0.4

desmethylclomipramine

300.8

C

0.15-0.3

0.4-0.5

Clonazepam

315.7

C

0.03-0.06

0.1-0.12

Clonidine

229

C

0.0003-0.0015

0.025

Clopenthixol (zu)

401

C

0.005-0.05 (0.1)

0.15-0.3

Clorazepic acid (clorazepat)

17

314.7

C

-

-

nordazepam

270.7

C

0.25-0.8

2

Cloxacillin

6

435.9

C

5-30
P85

-

Clozapine

18

326.8

C

0.2-0.6 (0.8)

0.8-1.3

Cobalt

`

58.9

K

0.0001-0.0022

-

Cocaine

19

303.4

C

0.05-0.3

0.9 L1-20

Codeine

299.4

C

T0.01-0.05
P0.05-0.25

0.3-0.5 L>1.6

Cogentin

C

0.08-0.125

0.48 L0.7

Colchicine

399.4

C

0.0003-0.0024 P0.003

0.005

Co-trimoxozole

20

344.8

C/M

-

-

Cresol

108

-

-

Cyanide

26

K

0.001-0.012 (0.15)

0.5 L2.4-5

Cyclizine

266.4

C

0.1-0.25 (0.03-0.3)

0.75 L15

norcyclizine

252.5

C

0.005-0.025

-

Cyclobarbital

236.3

C

5-10

10-15

Cyclobenzapine

275

C

0.003-0.036

-

Cyclopropan

42.1

80-180

-

Cyclosporine A

21

1203

K

T0.1-0.4

T0.4-0.5

Cytarabine (Ara C)

22

243.2

C

0.05-0.5

-

Dantrolene

314.3

C

0.4-1.5
T0.3-1.4
P1-3

-

Dapsone

248.3

C

0.5-5

10-20

Deferoxamine

406.8

C

3-15

-

ferrioxamine

1082.5

C

0.5-3

-

Desipramine

266.4

C

0.075-0.25

0.5

Dexfenfluramine

C

0.03-0.06

0.15-0.25

Dextromethorphan

271.4

C

0.01-0.04

L>3

Dextromoramide

392.5

C

0.075-5

-

Diazepam

284.7

C

0.125-0.75

1.5-5

nordazepam

23

270.7

C

0.2-1.8

-

Diazinon

304.3

C

-

0.05-0.1

Diazoxide

230.7

C

10-20

50-100

Dibenzepin

295.4

C

T0.025-0.15 P0.1-0.3

-

desmethyldibenzepin

C

0.2-0.4

3 L18

Dichlorodiphenyltrichloro-ethane

354.5

0-0.013

-

Dichloromethane

84.9

-

L280

Dichlorophenoxyacetic acid

221

C

-

200

Diclofenac

296.2

C

T0.05-0.5 P0.1-2.5

-

Dicoumarol

336.3

C

8-30 (50)

50-70

Dieldrin

380.9

C

0-0.0015

0.15-0.3

Diethylpropion

205.3

C

0.007-0.02

L5-4

Diflunisal

250.2

C

(9) 40-100

L600

Digitoxin

764.9

C

0.003-0.04

L0.32

Digoxin

24

780.9

C

T0.0007-0.0022

T0.002-0.004

Dihydrocodein

301.4

C

0.03-0.25

1 L2

Diltiazem

414.5

C

0.05-0.3

0.8 L6-7

Dimethadion

129.1

C

500-1000

1000

Dimethyltryptamine

188.3

C

0.001-0.1

-

Dinitro-O-cresol

25

198.1

C

1-5

30-60 L75

Diphenhydramine

225.4

C

0.025-0.11

0.2-2 L>10

Diphenoxilate

452.6

C

0.01

-

Dipyridamole

26

504.6

C

1-2 T0.1-1

4

Diquat

184.2

C/M

-

0.1

Disopyramide

27

339.5

C

2.5-7

-

nordisopyramide

297.5

C

8-10

Disulfiram

296.5

C

0.05-0.4

0.5-5

diethyldithiocarbamate

171.3

C

0.3-1.4

Divinyl-oxide (vinyl-ether)

70.1

L700

Domperidon

425.9

C

0.005-0.025 (0.04)

-

Dosulepin (Dothiepin)

295.4

C

0.05-0.15 (0.4)

L1.1

desmethyldosulepin

C

0.1-0.2

0.75

dosulepin-S-oxide

C

0.04-0.4

0.65-2

Doxapram

378.5

C

2.7-5.2

-

Doxazolin

451.5

C

0.08-0.15

-

Doxepin

279.4

C

0.1-0.25

nordoxepin

265.4

C

0.2-0.35

0.5-2

Doxorubicin

543.5

C

0.006-0.02

-

Doxycycline

444.5

C

5-10

30

Doxylamine

270.4

C

0.07-0.2

-

Dyphylline

254.3

C

6.5-14

-

Edrofonium

165.2

C

0.15-0.2

-

Enalapril

376.5

-

-

-

desethylenalapril

C

0.01-0.05 (0.1)

-

Encainide

352.5

C

-

-

methoxy-demethylencainide

0.06-0.28

-

o-demethylencainide

0.1-0.3

-

Endrin

380.9

C

0-0.003

0.03

Ephedrine

165.2

C

0.02-0.1

1

Epirubicin

543.5

C

0.01-0.05

-

Erythromycin

733.9

C

0.5-6 T0.5-1 P4-12

12-15

Estazolam

294.8

C

0.055-0.1

-

Ethambutol

204.3

C

0.5-5

6-10

Ethanol

46.1

K

0-25

1000-2000 L5000

Ethchlorvynol

144.6

C

0.5-8

20 L150

Ethinamate

167.2

C

5-10

100 L200

Ethosuximide

141.2

C

40-100

150 L250

Ethyl ether

74.1

C

500-1500

L(1400)-1900

Ethylene glycol

62.1

C

-

200

Etidocaine

276.4

C

0.5-1.5

1.6-2

Etodolac

287.4

C

20-50

-

Etoposide

588.6

C

T2-6 P8-14

-

Famotidine

337.4

C

0.02-0.06

-

Felodipine

384.3

C

0.001-0.012

-

Fenfluramine

231.3

C

0.05-0.15 (0.1-0.12)

0.3-0.7 L6

Fenoprofen

242.3

C

15-65

-

Fentanyl

336.5

C

0.01-0.05

-

Flecainide

414.4

C

T0.45-0.9 P0.75-1.25

T1-1.5

Flucytosine

129.1

C

T25-50
P50-100

100

Flumazenil

303.3

C

0.01-0.05 P0.2-0.3

-

Flunitrazepam

313.3

C

0.005-0.015

0.05

Fluoride

28

19

C/M

0.5
T0.08-0.15

T0.5-2 L2

5-Fluorouracil

29

130.1

C

0.05-0.3

0.4-0.6

Fluoxetine

309.3

C

0.09-0.5

norfluoxetine

30

295.3

C

(0.07) 0.15-0.5

-

Flupentixol

31

434.5

C

0.001-0.015

-

Fluphenazin

32

437.5

C

0.001-0.017

0.05-0.1

Flurazepam

33

387.9

0.0005-0.028

0.15-0.2 L0.5-17

desalkylflurazepam

288.7

C

0.04-0.15

0.2-0.5

Fluvoxamine

30

318.4

C

0.05-0.25

-

Furosemide

330.8

C

2-5 (10)

25-30

Ganciclovir

255.2

C

0.5-5 T0.2-1 P5-12.5

T3-5 P20

Gentamicin

34

463

C

T0.1-1.5 P5-10 (15)

T2 P12-15

Glibenclamide

494

C

0.03-0.35

-

Gluthetimide ()

217.3

C

2-12

12-20 L30

Gold ()

197

C

3-8

10-15

Guanethidine

198.3

C

0.01

-

Haloperidol

35

375.9

C

0.005-0.04

0.05-0.1 (0.5)

Halothane

197.4

K

22-200

L200

Heptabarbital ()

250.3

C

2-5

10

Heptobarbital

218.2

C

50-100

125-150

Hexachlorophene

406.9

C

0.003-0.65

L35

Hexapropymate

181.2

C

2-5

10-20

Hexobarbital

236.3

C

4-10

15 L50

Hydralazine

160.2

C

0.2-0.9

-

Hydrochlorothiazide

297.7

C

0.08-0.45

-

Hydrocodone

299.4

C

0.002-0.024

L0.2

Hydrogen Sulfide

34.1

C

-

L0.92

Hydromorphone

285.3

C

0.008-0.032

L>0.1

Hydroxychloroquine

335.9

C

T0.1-0.4 P0.5-2.0

L60

Hydroxyzine

374.9

C

P0.05-0.09

0.1 L39

Ibuprofen

206.3

C

15-30 (5-50)

100

Imipenem

317.4

C

T0.5-2 P20-75

-

Imipramine

280.4

C

0.045-0.15

0.4-0.5 L2

desipramine

266.,4

C

0.075-0.25 0.15-0.3

0.5 0.4-0.6

Indomethacin

357.8

C

0.8-2.5 (0.5-3)

4-6

Isoniazid

137.1

C

T0.2-1 P3-10

20

Isopropanol

60.1

K

-

200-400

acetone

58.1

K

-

400

Isosorbide dinitrate

236.1

C

0.003-0.018

-

isosorbide mononitrate

C

T0.2-0.5

-

Itraconazole

705.6

C

0.2-0.6 T1

-

Kanamycin

484.5

C

T1-4 P15-25

T5-10 P25-30

Ketamine

237.7

C

0.5-6.5

7

Ketanserin

395.4

C

0.015-0.2 P0.08-1

-

Ketazolam

368.8

C

0.001-0.02

-

nordazepam

270.7

C

0.2-0.6

1-2

Ketocanazole

23

531.4

C

T0.3-0.5 P3-10 (20)

-

Ketoprofen

254.3

C

1-5 P5-15

-

Ketorolac

255.3

C

0.22-3.5

-

Labetalol

328.4

C

0.025-0.2

0.5-1

Lamotrigine

256.1

C

0.5-4.5

-

Lead

36

207.2

C

up to 0.3

0.4-0.45

Lkevomepromazine

328.5

C

0.03-0.15

0.5

Lidocaine (Lignocaine)

234.3

C

1.5-5 (6)

7-14 L>25

monoethylglycinexyli-clide (MEGX)

206.3

C

0.07-0.175

-

Lithium

6.9

C

4-10 mg/l T0.6-1.2

mMol/l

T1.5 (2) mMol/l 14mg/l
L > 35mg/l

Loratadine

382.9

C

0.015-0.027

-

descarboethoxyloratadine

C

0.007-0.028

-

Lorazepam

321.2

C

0.02-0.25

0.3-0.6

Lormetazepam

37

335.2

C

0.001-0.01

-

Loxapine

327.8

C

0.01-0.03

L7.7

Lisergide (LSD)

323.4

C

-

0.001-0.004

Maprotiline

277.4

C

0.075-0.35

0.45-0.8 L2

desmethylmaprotiline

263.4

C

0.1-0.4

0.75-1

Medazepam

270.8

C

0.01-0.15 P0.1-0.5

0.6

nordazepam

270.7

C

0.2-0.6

1-2

Mefenamic acid

241.3

C

0.3-20

-

MEGX (liver test)

206.3

C

T0.07-0.175

0.05

Meperidine

247.4

C

0.07-0.8

5
L>5

Mephenesin

182.2

C

3-10

-

Mephenytoin

218.3

C

desmethylmephenitoin

C

15-40

50

Mepivacaine

246.4

C

2-4 (5.5)

6-10 L50

Meprobamate

218.3

C

10-25

50 L140

6-Mercaptopurine

38

152.2

C

0.03-0.08

1-2

Mercury (organic)

39

200.6

K/M

0-0.01

0.1-0.3
L0.4-22

Mercury (inorganic)

200.6

K

0-0.08

0.2 L>0.6

Mesoridazine

386.6

C

1.2-3.5

L3

Mesuximide

203.2

C

0.04-0.08

-

N-desmethylmesuximide

189.2

C

10-30 (40)

40

Metformin

129.2

C

1-4

45-70

Methadone

40

309.5

C

0.1-0.75 (0.01-1.1)

1-2 L>4

Methamphetamine

149.2

C

0.01-0.05

0.2-1 (5) L10-40

Methanol

32

K

-

200 L>900

Methaqualone

250.3

C

0.5-3

5-8 L>10

Methazolamide

236.3

C

40

-

Methocarbamol

241.2

C

25-40

-

Methotrexate

41

454.5

C

active 0.005

T0.2 (48 hrs)

Methotrimeprazine

328.5

C

0.02-0.14

-

Methoxsalen

216.2

C

0.1-0.2 T0.025-0.1

P0.1-0.4

1

Methoxyflurane

165

30-200

-

Methyldopa

211.2

C

1-7.5

10

Methylendioxyam-phetamine (MDA)

179.2

C

-

L4-10

Methylendioxymethylamphetamine (XTC.MDMA)

193

C

0.1-0.35

0.5

Methylfentanyl

350.5

C

-

L0.002-0.011

Methylphenidate

233.3

C

0.01-0.06

0.8 L2.3

Methylprylon

183.3

C

5-15

30-60 L100

Metiamide

C

0.01-0.06

-

Metoclopramide

299.8

C

0.04-0.1

0.1-0.2

Metoprolol

267.4

C

0.1-0.6 T0.02-0.34

1

Metronidazole

171.2

C

10-30

200

Mexiletin

179.3

C

1-2 T0.5-2

1.5-3

Mianserin

264.4

C

0.02-0.07

-

desmethylmianserin

250.3

C

0.04-0.125

0.3-0.5 L2

Midazolam

42

325.8

C

0.08-0.25

1-1.5

Milrinon

211.2

C

0.15-0.25

0.3

Moclobemide

268.7

C

T0.02-0.04 P1.5-2.5

-

Morphine

43

285.4

C

0.08-0.12

0.15-0.5 L0.05-4

Nalidixic acid

232.2

C

M

10-30

50-200

40-50

-

Naloxone

327.4

C

0.01

-

Noproxen

44

230.3

C

25-75 (90)

-

Netilmicin

45

475.6

C

T1-3 P6-12 (12)

T4 P12 (15)

Nicardipine

479.5

C

0.035-0.135

-

Nicotine

46

162.2

T0.001-0.275

cotinine ()

176.2

C

P0.025-0.35

0.3-1 L5

Nifedipine

346.3

C

0.025-0.15 T0.01-0.02

-

Nikkel

58.7

C

M

0.0015-0.005

0.0005-0.006

-

-

Nimustine

272.7

C

0.0002-0.0005

-

Nitrazepam

47

281.3

C

0.03-0.12

0.2-0.5

Nitrofurantion

238.2

C

M

0.5-2

10-400

3-4
(child 2)
-

Nitropruside

218

C

thiocyanate

57.1

C

6-30

60
L200

Nizatidine

331.5

C

0.15-1

-

Nomifensine ()

48

238.3

C

T0.02-0.06 P0.2-0.6

0.8-1

Nordazepam

270.7

C

0.2-0.8 (1.8)

1.5-2

Norfloxacin

319.3

C

0.5-5

-

Nortriptyline

263.4

C

0.075-0.25

0.5

Obidoxim

359.2

C

1-10

-

Ofloxacin

361.8

C

1-4 T0.05-5 P1-7

-

Ondansetron

293.3

C

0.03-0.3

-

Opipramol

363.5

C

0.05-0.2 (0.5)

0.5-2

Orphenandrin

49

269.4

C

tofenacin

255.4

C

0.05-0.2

0.5-2
L4-8

Oxazepam

286.7

C

(0.15) 1-2

3-5

Oxcarbazepam

252.3

C

12-30 (40)

hydroxycarbazepine

C

0.1-1

50

Oxprenolol

265.4

C

5-10

2-3

Oxtetracycline

460.5

C

0.01-0.1

30

Oxycodone

315.4

C

10-100

0.2-5

Oxyphenbutazone

324.4

C

-

Pancuronium

652.8

C

0.1-0.6

L1.6

Papaverine

339.4

C

0.2-0.6 (2)

-

Paracetamol (Acetaminophen)

50

151.2

C

10-20 (2.5-25)

T75-100
P100-500
TL160

Paraldehyde

51

132.2

C

30-300

400
L>500

acetaldehyde

CK

-

100-125

Paramethadione

157.2

C

1.1-5

-

Paraquat

186.3

CM

-

0.05 L2

Parathion

52

291.3

C

-

0.01-0.05

Paroxetine

329.3

C

0.01-0.075 P0.03-0.15

-

Pefloxacin

333.4

C

T0.1-6 P5-10

25

Penbutolol

291.4

C

0.3-0.7

-

Penfluridol

524

C

0.004-0.025

-

Penicillin (benzyl)

6

334.4

C

1-10

-

Pentachlorophenol

266.4

C

0-0.1

30 L>45

Pentazocine

285.4

C

0.05-0.2 (0.5)

1 L>2

Pentobarbital

53

226.3

C

1-3 (25-40)

5-10

Perazine

339.5

C

0.025-0.1

0.5

Periciazine

365.5

C

0.005-0.03

0.1

Perphenazine

54

404

C

0.0004-0.03

0.05-0.1

Pethidine

247.3

C

0.2-0.8

1-5 L8

norpenthidine

C

0.5

Phenacetin

179.2

C

5-20

50

Phenazone (antipyrine)

55

188.2

C

5-25

50-100

Phencyclidine (PCP)

243.4

C

-

0.007-0.24
L1-5

Phendimetrazine

191.3

C

0.02-0.24

-

Phenelzine

136.2

C

0.001-0.002

L>1.5

Phenmetrazine

177.3

C

0.04-0.25

0.5 L4

Phenobarbital

232.2

C

(10) 20-40

60-80
L100-150

Phenol

94.1

-

L90

Phenprocoumon

280.3

C

1-3

5

Phensuximide

189.2

C

4-10 P10-20

80

Phentermine

149.2

C

0.09

-

Phenylbutazone ()

308.4

C

50-150

200-250 L400-500

Phenylephrine

167.2

C

0.03

-

Phenylpropanolamine

151.2

C

0.03-0.5

L48

Phenytoine

252.3

C

8-20 6-14

20-30 15 L100

c

C

0.2-2

2

Pimozide

461.6

C

0.001-0.02

-

Pindolol

248.3

C

0.01-0.07 (0.15)

0.7

Pipamperone

375.5

C

0.1-0.4

0.5-0.6

Piperacilline

517.6

C

T1-5 P20-70

-

Pipotiazine

475.7

C

0.001-0.06

0.1

Pirenzepine

351.4

C

0.2-0.3

-

Pirmenol

338.5

C

1-3

-

Piroxicam

331.3

C

0.85-13.5 P2-20

-

Platinum

195.1

C

0.5-5 P10-30

30 T10

Polythiazide

439.9

C

2-7

-

Prazepam

324.8

C

0.01-0.04

-

nordazepam

270.7

C

0.2-0.8

1-2

Prazocin

383.4

C

0.001-0.075

-

Prilocaine

220.3

C

0.5-2

5

Primidone

218.3

T5-12

15-20

phenobarbital

232.2

C

20-40

60-80

Probenecid

56

285.4

C

40-60 100-200

-

Procainamide

235.3

4-8

10-15
L>20

N-acetylprocainamide

277.4

C

2-12

40

Procaine

236.3

5-15

20-40

Prochlorperazinde

373.9

C

0.01-0.04

0.2-0.3 L5

Procyclidine

287.4

0.08-0.63

L7.8

Promazine

284.4

C

0.1-0.4

2-3 L>5

Promethazine

284.4

C

0.1-0.4

1-2

Propafenone

57

341.5

(0.2) 0.4-1.6 (1.6)

1.1-2

norpropafenone

415.5

C

0.07-0.7

-

Propericiazine

C

T0.005 P0.05

0.1

Propofol

178

K

2-5

-

Propoxyphen (dextro)

339.5

0.1-0.75

1

norpropoxyphen

325.5

C

0.1-0.15

2

Propranolol ()

58

259.3

C

T0.05-0.15 P0.1-0.3

1-2 L4-10

Propylene glycol

76.1

C

0.05-0.5

1000-2000

Propylhexedrine

155.3

C

0.01

L2-3

Protionamid

180.3

C

T0.5 P3-8

-

Protriptyline

263.4

C

0.07-0.17 (0.38)

0.5-1

Pseudoephedrine

165.2

C

0.5-0.8

L19

Pyrazinamide

123.1

C

30-75

-

Pyridostigmine

181.3

C

0.05-0.17

-

Quazepam

368.8

C

0.01-0.15

-

Quinidine

324.5

C

(1) 2.5-5

(6)-10
L30-50

Quinine

324.5

C

2-9.5

10
L12

Ranitidine

314.4

C

(0.05) 0.15-0.25

-

Rifabutin

846

C

T0.05 P0.15

Rifampicin

823

MIC 1-5

-

desacethylrifampicin

808.9

C

T0.1-1 P4-10

T2-4
P12-20

Risperidon

410.5

C

0.01-0.09

-

hydroxyrisperidon

C

0.01-0.1

-

Salbutamol

239.4

C

0.004-0.015 (0.03)

0.025-0.1

Salicylic acid

59

138.1

C

20-300

300-500

L500-1000

Scopolamine

303.4

C

0.0003

-

Secobarbital

238.3

C

1-5

6-10 L10-50

Sertraline

306.2

C

0.05-0.25

-

Silver ()

60

107.9

K

0-0.005

0.06-0.6

Sotalol

272.4

C

0.8-5

-

Spironolactone

416.6

C

0.1-0.5

-

canrenone

C

0.05-0.25

-

Streptomycin

581.6

C

T1-5 P15-40

T5
P40-50

Strychnine

334.4

C

-

0.075-0.1
L0.2-2

Sufentanil

386.6

C

0.0005-0.011

-

Sulfaquanidine

214.2

C

30-50

-

Sulfamethoxazole

253.3

C

40-60 (100-200)

200

Sulfanilamide

172.2

100-150

-

Sulfonamides

CM

T35-75 P80-150

200

Sulindac

356.4

C

0.5-5

-

Sulindac-sulfide

340.4

C

1-4

-

Sulpiride

341.4

C

0.04-0.6 (P0.15-0.75)

-

Sultiam

290.4

C

1-12

12-15
L20-25

Suramine

1407.2

10-250

300

Tacrolimus (FK506)

804

K

T0.003-0.015

P0.01-0.025

T0.012-0.15

Tamoxifene

371.5

C

0.05-0.5

-

Teicoplanin

189.4

C

T10-40 (5-50)

200

Temazepam

300.7

C

0.3-0.9 T0.02-0.1

1

Terbinafine

291.4

C

T0.01-0.03 P0.5-3

-

norterbinafine

C

P0.4-0.8

-

Terbutaline

225.3

C

0.001-0.006

L0.04

Terphenandrine

471.7

C

0.0015-0.0045

-

Tetrachloroethylene

165.9

C

-

L4-5

Tetracycline

444.4

C

5-10 T1-5

30

Thallium

61

204.4

K

-

0.1-0.5

Theobromine

180.2

C

10-15

20

Theophilline

180.2

C

8-20 5-10

25-30 1
5 L50-250

Thiazinamium

299.5

C

0.05-0.15

0.3

Thiocyanate

62

58

C

1-12 (30)

35-40 (100)
L200

Thiopental

63

242.3

C

1-5 (25-40)

10 (40-50)

L10-100

pentobarbital

63

226.3

C

5-10

10-15

Thioridazine

64

370.6

C

0.2-1

2 (5)

mesoridazine

386.6

C

0.3

-

sulforidazine

402.6

C

0.75-1.5

3

Thiothixene

443.6

C

T0.001-0.02 P0.01-0.1

0.1

Thiaprofenic acid

260.3

C

15-35

-

Timolol

316.4

C

T0.005-0.05 P0.02-0.1

-

Tin ()

118.7

C

0.12-0.14

-

Tobramycin

65

467.5

C

T0.5-1.5 P5-10 (15)

T2 P15

Tocainide

193.2

C

4-10

25

Tofenacine

255.4

C

P0.025-0.1

0.5-1

Tolbutamide

270.3

C

45-100

500 L600

Tolmetin

257.3

C

10-80

60

Tolueen ()

92.1

K

-

L10

Tranylcypromine

133.2

C

0.05

-

Trazodone

371.9

C

0.5-2.5 T0.3-1.5

P1.5-2.5

4 L15

Triamtereen

253.3

C

T0.01-0.1 P0.05-0.2

-

Triazolam

343.2

C

0.002-0.02

-

Tribromo-ethanol

282.8

K

-

L90

Trichloro-ethane

133.4

K

-

L100-1000

Trichloroethanol

149.4

C

5-15

40-70
L250

Trichlorophenoxyacetic acid

255.5

C

-

200

Trifluoperazine

407.5

C

0.005-0.05

0.1-0.2

Triflupromazine

352.4

C

0.03-0.1

0.3-0.5

Trihexyphenidyl

301.5

C

0.05-0.2

0.5

Trimethadione

143.1

C

500-1000

1000

Trimethobenzamide

388.4

C

1-12

-

Trimethoprim

290.3

CM

1.5-2.5 (5-10)

15-20

Trimipramine

294.4

C

0.07-0.17 (0.3)

0.5
L8.7

Tripelennamine

255.4

C

0.06

L10

Triprolidine

278.4

C

0.004-0.045

-

Tropisetron

20-30
P50-100

-

Tubocurarine

646.2

C

0.04-3 (6)

-

Valnoctamide

143.2

C

5

40

Valproic acid

144.2

C

50-100

150-200

Vancomycine

1449.2

C

10-20
T8-12
P20-35

P40

Verapamil

66

454.6

C

0.09-0.35

0.9
L4-8

norverapamil

C

0.15-0.6
T0.05-0.4

1

Vigabatrine

129.6

C

T5-150

-

Vinblastine

811

P0.25-0.4

-

Vincristine

824.9

P0.3-0.4

-

Vinylbital

224.3

C

5-10

15

Warfarin

308.3

C

1-7
T0.3-3
P5-10

10-12

Xylene ()

106.2

K

-

L3-40

Zidovudine

267.2

C

T0.1-0.3 P1-1.5

2-3

Zolpidem

307.4

C

0.08-0.15

0.5

Zopiclone

388.8

C

0.01-0.05
P0.04-0.07

,

- (, ) , .

- (, ) , .

- (, ) , , , .

, /, / .

:

  • -
  • -
  • -
  • - ,
  • -
  • - , -
  • L -
  • -
  • -

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:

  • - , ,
  • - ( )
  • - (, .)
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  • -
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, , , . , , , .

, , - . , .

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. : , ..

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. .

1. Acemazolamide - 4-5 /

2. Acetone - : 5-20 / ; 600 /; 40-150 / , 100-700 / ; 325-450 / , 450-900 / ; 50 / , 2200 / . 200-300 / .

3. Acetylsalicylic acid. . in vitro .

4. Acyclovir. : 0.2-0.5 /; 0.5-1.0 /, ED50 0.01-2.0 /.

5. Aluminium. 0.07 /. .

6. Penicillin Cephalosporin. ( ).

7. Amsacrine. . 1 48 -20 . 0.1-0.5 / . .

8. Arsenic. As (1) , As (V). : 0.2-1.0 /, - 1 /.

9. Azathioprine. 6-(50 1,4-di-thiotheritol 1 M ). .

10. Bromide. 30 /. 75-100 /. 50-150 /. 200 /.

11. Bromperidol. LLQ .

12. Bupivacaine. 0.25-0.75 /.

13. Cffeine. 8-15 /. 95% 5 /, 55 - 5-19 /. 12 /. 20-30 /, 50 /.

14. Carbamazepin. 7-12 /. 24 /. 25 / : . - / =0.1. .

15. Carbon monoxide. 0-5%, 15%, 8-10%, 20-30 %, 50%.

16. Clobazam. . N-.

17. Clorazepate. , .

18. Clozapine. 0.125-0.4 /. 0.5-0.8 /. 0.5 / . .

19. Cocaine. - . 2-3 .

20. Co-trimoxazole. trimethoprim: 1.5-2.5 /, 20 /; : 40-60 /, - 400 /; : 100-200 /. Phenmocystis carinii: 100-200 /, 5-10 /.

21. Cyclosporine A. 350-500 /.

22. Cytarabine. 500 , Ara U, .

23. Diazepam. 0.25-0.5 /, 0.125-0.25 /, , 1.0-1.5 /, () 24 , . , , .

24. Digoxin. 5-6 . 2-3 3,5 /.

25. Dinitro-ortho-cresol. DNOC 40-60 /, 60-80-/, 80-100-/, 100 /.

26. Dipyridamole. ( 2,5 ) 1-2 /, 1,75 /.

27. Dispopyramid. 2.5-3.5 /, 3.5-7.0 /, 20% , .

28. Fluoride. 0.08-0.15 / 24 . 24 . 0.04 /. , . .

29. 5-Fluorouracil. 0.3-0.6 / ( 0) - , 0.8 / ( 1) - 1 / .

30. Fluxetine / Fluvoxamide. . , .

31. Flupentixol. LLQ.

32. Fluphenazine. 0.0025-0.005. LLQ.

33. Flurazepam. 0.007 /, 0.012-0.015./, 0.015 , , 0.04-0.15 /, 0.2 /.

34. Gentamicin. ( 15 ), 0.5 .

35. Haloperidol. 0.008 , 0.01-0.05 /. 0.05 /. LLQ=0.005 /.

36. Lead (Pb). ( ) 0.3 , 0.25 /, 0.45 / - , 0.4 /. - 0.5 /, - 0.7-1.0 /.

37. Lormetazepam. LLQ.

38. 6-Mercaptopurine. 0.04-0.3 /; , .

39. Mercury (Hg) . 0.01 / . 0.02-0.05 / . .

40. Methadone. 0.1-0.3 /. 0.2-0.75 , 1 /, 1 . , , 1 /. 2-4 . . 0.04-0.3, 0.5, 1, 10-40 .

41. Methotrexate. 5-10 /, , . : 0.5 / 48 , 0.2 / 48 , 0.1 / 72 24 .

42. Midazolam. 0.08 /. 0.04 /. 0.03 / 0.11 / . 60-80%.

43. Morphine. - ( , , ). 0.3 / . 1-2 , 4 . 0.08-0.12 /. 0.04 /. 6- - ( ). 0.15 /, 0.15-0.5 /, .

44. Naproxen. 250 /.

45. Netilmicin. ( 15-18 ), 1 . 12-15 /.

46. Nicotine / Cotinine. : 0.003-0.005 /, 0.03-0.035 /. 0.175-0.275 /, 0.25-0.34 /. : 0.001-0.002 /, 0.001-0.005 /. 0.001-0.01 /, 0.025-0.05 /. , , 0.004-0.031 /.

47. Nitrazepam. . 0.05-0.12 /, 0.03-0.05 /.

48. Nomifensine. : 2-6 /, 0.2-0.6 .

49. Orphenandrine. . .

50. Paracetamol. 4 . 75-100 /, 100-300 /, - 300 /.

51. Paraldehyde. 30-100 /, 100-300 /, 200-300 /.

52. Parathion. , ; . . 0.003-0.2 /, .

53. Pentobarbital. ( ) 25-40 /. .

54. Perphenazine. 0.0006-0.0011 /. 0.012 / LLQ 0.002 /.

55. Phenazone. (). : 10 , 10 , .

56. Probenecid. 40-60 /; 100-200 /.

57. Propafenone. 0.2-1.1 , - 0.8 /. 3 : 6-10 . 1.1 / ( ).

58. Propronolol. 0.025-0.05. . 0.1 /. -- 0.3 / -.

59. Salicylic acid. : 200-300 /, : 100-250 /, 50-125 /, , 30-100 /, 50-150 /, 400-500 /, 300 /. ( ) 6 800 /, 12 700 /, 24 500 /.

60. Silver (Ag). 0.06-0.6 /.

61. Thallium. : 0.25-0.5 /24 , 0.1-0.5 / . 0.1 /24 . : 1 / ( 48 ).

62. Thiocyanate. : 1-4 /, 3-12 /, : 6-30 /. 35-50 /, 60 /, : 60-100 /, 200 /.

63. Thiopental. EEG 25-40 /, , 5-10 /, 10-15 /.

64. Thioridazine + mesoridazine + sulforidazine. : 0.75-1.5 /, 3 /. Thioridazine-ringsulfoxide: 0.9 /.

65. Tobramycin. ( 15 /) 0.5 /. ( 12 /).

66. Verapamil. 1 /, ; AV- 1 + . 20% .

  1. Donald R.A. Uges TIAFT Bulletin of the international Association of Forensic Toxicologist, VOLUME 26 number 1 SUPPLEMENT. 1996.
  2. Winek C.L. Drug and chemical blood-level data 1994 in Winek"s Toxicological Annual, 1994.
  3. Donald R.A. Uges, Response to Compilation of Therapeutic Drug Levels, Letter to the Editor, TIAFT Bulletin 1996, 26(1):18-19.
  4. Jones G. to Compilations of Therapeutic Drug Levels, Letter to the Editor, TIAFT Bulletin 1995; 25 (4) : 15-18.

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